End-to-End Workflow Integration
From initial concept design and computational simulation (CFD/FEA) to rapid prototyping, and biological validation—we manage the complete development lifecycle in-house.
High-Precision Prototyping and Fabrication
Our prototyping facilities, photo- and soft-lithography (PDMS) capabilities, along with advanced micro-actuation systems, enable rapid and high-precision iterative development of microfluidic chips, Organ-on-a-Chip, and Lab-on-a-Chip platforms.
Advanced Characterization and Analytics
Our infrastructure includes high-resolution optical and fluorescence microscopy, micro-PIV flow characterization, and integrated sensing.
PDMS–Glass Microfluidic Chips via SU-8 Photolithography and Soft Lithography
We deliver high-precision, custom microfluidic devices using standard-setting PDMS–glass hybrid fabrication technology:
- SU-8 Photolithography: High-resolution master molds are fabricated on silicon wafers using SU-8 negative photoresist to create precise microchannel geometries.
- Soft Lithography Molding: Polydimethylsiloxane (PDMS) is cast and cured over the master mold, accurately replicating sub-micron to millimeter-scale channel features.
- Plasma Bonding: The patterned PDMS block undergoes oxygen plasma surface activation and is covalently bonded to a high-quality glass slide, forming a robust, leak-free seal.
PDMS–Glass Microfluidic Chips via Stereolithography and Soft Lithography
We deliver high-precision, custom microfluidic devices leveraging additive manufacturing for rapid master mold prototyping:
- LCD Stereolithography (SLA/MSLA): Master molds are high-resolution 3D printed substrates using epoxy-based resins and LCD stereolithography.
- Soft Lithography Molding: Polydimethylsiloxane (PDMS) is cast and cured over the 3D-printed epoxy resin mold, accurately replicating microchannel networks.
- Plasma Bonding and Integration: The patterned PDMS block undergoes oxygen plasma surface activation and is covalently bonded to a high-quality glass slide, forming a robust, leak-free seal.
PMMA-PSA-PMMA Microfluidic Chips via Laser-Ablation and Assembly
We fabricate high-precision macrofluidic systems using laser micromachining and multi-layer bonding technologies:
- Laser Ablation and Surface Patterning: Substrates are precisely structured using high-resolution laser cutting and rastering to create intricate channels, chambers, and functional surface topologies.
- Precision Multilayer Assembly: Thermoplastic (PMMA) layers and pressure-sensitive adhesives (PSA) are aligned and stacked into robust sandwich architectures.
- Functional Membrane and Layer Integration: The modular assembly process enables seamless integration of specialized filtration membranes, electrodes, or custom functional interlayers.
PMMA-PMMA Microfluidic Chips via Laser-Ablation and Thermal Bonding
We manufacture pure thermoplastic microfluidic systems using laser micromachining and solvent/PSA-free thermal bonding:
- Laser Ablation and Surface Patterning:PMMA substrates are precisely structured using high-resolution laser cutting and rastering to create custom fluidic systems.
- Precision Multilayer Assembly: ndividual PMMA layers are accurately stacked and aligned to form complex, multi-level sandwich architectures tailored for biological applications.
- Adhesive-Free Thermal Bonding: The aligned PMMA layers are covalently joined via direct thermal bonding, ensuring bio-inert channel surfaces and eliminating chemical leaching risks.